Beyond Barriers

A novel technology platform
for the delivery of therapeutics
across biological barriers

Gate2Brain

The solution

Gate2Brain
Technology

Gate2Brain (GB2) uses a novel technology platform for the delivery of therapeutics. Our platform is based on three families of peptide shuttles that improve the biopharmaceutical properties of cargoes such as small molecules, peptides, nanoparticles, proteins and antibodies in vitro and in vivo when conjugated to them.

The G2B technology platform is applicable to therapeutic areas in which biological barriers hinder the delivery and activity of drugs.

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About us

Gate2Brain is a biotech company focused on the development of therapeutics that efficiently cross biological barriers such as the blood-brain barrier. We pursue our goals using a radically innovative peptide-based patented technology platform.

Technology

Gate2Brain (G2B) has a proprietary novel technology platform for the delivery of therapeutics across biological barriers.

Medicines beyond barriers

We go beyond physiological and disease barriers, as our portfolio of peptide shuttles cover barriers such as the blood-brain,
blood-retinal, skin and tumor barriers.
We go beyond economic barriers, such as the lack of investment for the development of pediatric drugs. We go beyond societal barriers to provide medicines for everyone, everywhere.

Clinical Focus

Therapeutic
Proof of Concept

Our G2B therapeutic-peptide shuttle conjugates carry the drug cargo candidates to the target site in which the disease arises. G2B-002, our flagship product and proof-of-concept of the technology, offers a new therapeutic approach with improved biopharmaceutical properties and potent activity against rare pediatric cancers.

Our objective is for G2B-002 to reach Phase 1 clinical trials and thus have a high social impact focused on the unmet medical needs of:

Rare illnesses
Pediatric patients
Oncologic diseases

G2B-002 shows potent preclinical activity for rare pediatric cancer indications such as pediatric high-grade gliomas, DIPG, Ewing sarcoma, rhabdomyosarcoma and neuroblastoma.

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News & Media

Welcome to our news section, which provides a selection of our coverage in the media, industry, latest developments, plus videos, and more.

Gate2Brain’s Bridge Fundraising Round

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  Click on this image to register on Eventbrite for Gate2Brain Bridge Fundraising Round Online…

EIC and J&J Healthcare Investor Day

Thrilled to announce that Gate2Brain, as an EIC beneficiary - European Innovation Council and SMEs Executive…

Gate2brain or the innovative solution for pediatric brain tumors

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Article by Ana M. González The Catalan startup was born to promote a technology that helps drugs reach…

Gate2Brain 4-Year Journey

Our special annual magazine, which takes you through the 4-year journey of Gate2Brain …

Jump4Women – Trip to Boston

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We are incredibly honored to have been part of a group of 19 women entrepreneurs who recently traveled…

Back to Work with Peptides

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  These late August days have been busy for us as we've been attending two peptide conferences.…

Fernando Albericio – Meet the Advisory Board

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We are continuing to introduce the remarkable individuals who make up Gate2Brain’s external advisory…

Breaking Barriers in Science: The Journey of Meritxell Teixidó and Gate2Brain

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Interview with Meritxell Teixidó, PhD, CEO & CSO, Gate2Brain By Caitlin Dolegowski, Marketing Manager,…

Gate2Brain and Intact Barrier Brain Tumors: A Ray of Hope in the Fight against DIPG

On the occasion of World Brain Day Meritxell Teixidó, CEO & CSO of Gate2Brain, analyzes the scientific…

Alejandro Sosnik – Meet the Team

Recently, a new member joined our team. We're so grateful to have such an awesome crew!!. It’s a pleasure…
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Making therapies a reality for patients by addressing unmet medical needs.

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Improving patients’ quality of life using a technology that provides superior drug transport efficacy.

Go Beyond Barriers & Contact Us

Barcelona Scientific Park
Baldiri Reixac, 4-8, Torre I
08028 Barcelona, Spain
info@gate2brain.com

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