Gate2Brain, a Technology Keybox of BBB-Shuttle Peptides

Gate2Brain

G2B therapeutic-peptide shuttle conjugates are new chemical entities, permeable, non-antigenic, stable, receptor-specific, soluble, non-invasive, and cost-effective products that can cross biological barriers (such as the blood-brain barrier).

Unique properties conferred by
Gate2Brain technology

  • 1

    Ability to penetrate barriers. Our peptides cross biological barriers, such as the blood-brain barrier, to bring therapeutic cargoes to their targets.

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Gate2Brain
Gate2Brain
  • 2

    Non-antigenicity. Our proprietary peptides are not immunogenic, minimizing the likelihood of immune reactions against G2B therapeutic-peptide shuttle conjugates.

  • 3

    Protease resistance. Our proprietary peptides bear chemical modifications that increase their half-life up to days, maximizing the area-under-the-curve of G2B therapeutic-peptide shuttle conjugates at their biological targets.

    3

Gate2Brain
Gate2Brain
  • 4

    Receptor specificity. Our proprietary peptides cross biological barriers through receptor-mediated transcytosis.

  • 5

    Water solubility. Our proprietary peptides improve the solubility of practically insoluble small molecule cargoes, making them suitable for human administration.

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Gate2Brain
Gate2Brain
  • 6

    Non-invasiveness. Our technology allows the administration of therapeutic cargoes by conventional administration routes.

  • 7

    Cost-effectiveness. Our therapeutic-peptide shuttle conjugates can be produced using low cost and easily scalable processes.

    7

Gate2Brain

Gate2Brain, a Technology Keybox of BBB-Shuttle Peptides

G2B therapeutic-peptide shuttle conjugates are new chemical entities, permeable, non-antigenic, stable, receptor-specific, soluble, non-invasive, and cost-effective products that can cross biological barriers (such as the blood-brain barrier).

Gate2Brain

Unique properties conferred by
Gate2Brain technology

Gate2Brain
Gate2Brain
Gate2Brain
Gate2Brain
Gate2Brain
Gate2Brain
Gate2Brain