Beyond Barriers

A novel technology platform
for the delivery of therapeutics
across biological barriers

Gate2Brain

The solution

Gate2Brain
Technology

Gate2Brain (G2B) uses a novel technology platform for the delivery of therapeutics. Our platform is based on three families of peptide shuttles that improve the biopharmaceutical properties of cargoes such as small molecules, peptides, nanoparticles, proteins and antibodies in vitro and in vivo when conjugated to them.

The G2B technology platform is applicable to therapeutic areas in which biological barriers hinder the delivery and activity of drugs.

About us

Gate2Brain is a biotech company focused on the development of therapeutics that efficiently cross biological barriers such as the blood-brain barrier. We pursue our goals using a radically innovative peptide-based patented technology platform.

Pipeline and Therapeutic Proof of Concept

G2B-002, the first therapeutic proof of concept of our technology platform, is aimed mainly at the treatment of rare pediatric solid tumors.

Medicines beyond barriers

We go beyond physiological and disease barriers, as our portfolio of peptide shuttles cover barriers such as the blood-brain,
blood-retinal, skin and tumor barriers.
We go beyond economic barriers, such as the lack of investment for the development of pediatric drugs. We go beyond societal barriers to provide medicines for everyone, everywhere.

Clinical Focus

Therapeutic
Proof of Concept

Our G2B therapeutic-peptide shuttle conjugates carry the drug cargo candidates to the target site in which the disease arises. G2B-002, our flagship product and proof of concept of the technology, offers a new therapeutic approach with improved biopharmaceutical properties and potent activity against rare pediatric cancers.

Our objective is for G2B-002 to reach Phase 1 clinical trials and thus have a high social impact focused on the unmet medical needs of oncology, pediatric and rare diseases.

G2B-002 shows potent preclinical activity for rare pediatric cancer indications such as pediatric high-grade gliomas, DIPG, Ewing sarcoma, rhabdomyosarcoma and neuroblastoma.

Gate2Brain

News & Media

Welcome to our news section, which provides a selection of our coverage in the media, industry, latest developments, plus videos, and more.

CaixaImpuls

Gate2Brain as alumni at Caixa Impulse Validate

On Monday 4th of October, Gate2Brain gave a talk at the Caixa Impulse Validate session. An acceleration…
BioSpain2021

Gate2Brain attending BioSpain 2021

Gate2Brain attending BioSpain 2021Gate2Brain will be participating at the 10th edition of BioSpain…
36 startups españolas brillaran en South Summit 2021

These are the 36 Spanish startups that will shine at South Summit 2021

South Summit, el evento de referencia en España organizado por Spain Startup vuelve con más fuerza…
Top Spain Medical Startups 2021

Gate2Brain among the 101 top medical startups in Spain

101 Top Medical Startups and Companies in Spain (2021) This article showcases our top picks for the…
Foment shows how the leadership of a new generation of female innovators is already a reality at # MWC21Foment del Treball

Foment shows how the leadership of a new generation of female innovators is already a reality at # MWC21

En el marc de la celebració dels seus 250 anys i de la seva col·laboració amb la Fundació Mobile…
Innovation & Scalability for the new generations

Innovation & Scalability for the new generations

On the occasion of the Mobile World Congress Barcelona & 4YFN, Gate2Brain will be participating tomorrow…
round table at 2021 Worldwide Congress Barcelona & 4YFN
Entrepreneurship for Life Sciences and Healthcare Startups Spring Cohort 2021

Gate2Brain attended from March to June the UCFS’s Entrepreneurship for Life Sciences and Healthcare Startups Spring Cohort 2021

Gate2Brain attended from March to June the Entrepreneurship for Life Sciences and Healthcare Startups…
Gate2Brain selected to form the Spanish Delegation for AnglonordiScience Conference 2021

Gate2Brain selected to form the Spanish Delegation for Anglonordic Life Science Conference 2021

Anglonordic is the only life science conference in the UK that is exclusively for European investors…

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Gate2Brain
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Making therapies a reality for patients by addressing unmet medical needs.

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Improving patients’ quality of life using a technology that provides superior drug transport efficacy.

Go Beyond Barriers & Contact Us

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Barcelona Scientific Park
Baldiri Reixac, 4-8, Torre I
08028 Barcelona, Spain
info@gate2brain.com

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