Beyond Barriers

A novel technology platform
for the delivery of therapeutics
across biological barriers


The solution


Gate2Brain (G2B) uses a novel technology platform for the delivery of therapeutics. Our platform is based on three families of peptide shuttles that improve the biopharmaceutical properties of cargoes such as small molecules, peptides, nanoparticles, proteins and antibodies in vitro and in vivo when conjugated to them.

The G2B technology platform is applicable to therapeutic areas in which biological barriers hinder the delivery and activity of drugs.

About us

Gate2Brain is a biotech company focused on the development of therapeutics that efficiently cross biological barriers such as the blood-brain barrier. We pursue our goals using a radically innovative peptide-based patented technology platform.

Medicines beyond barriers

We go beyond physiological and disease barriers, as our portfolio of peptide shuttles cover barriers such as the blood-brain,
blood-retinal, skin and tumor barriers.
We go beyond economic barriers, such as the lack of investment for the development of pediatric drugs. We go beyond societal barriers to provide medicines for everyone, everywhere.

Clinical Focus

Proof of Concept

Our G2B therapeutic-peptide shuttle conjugates carry the drug cargo candidates to the target site in which the disease arises. G2B-002, our flagship product and proof of concept of the technology, offers a new therapeutic approach with improved biopharmaceutical properties and potent activity against rare pediatric cancers.

Our objective is for G2B-002 to reach Phase 1 clinical trials and thus have a high social impact focused on the unmet medical needs of oncology, pediatric and rare diseases.

G2B-002 shows potent preclinical activity for rare pediatric cancer indications such as pediatric high-grade gliomas, DIPG, Ewing sarcoma, rhabdomyosarcoma and neuroblastoma.


News & Media

Welcome to our news section, which provides a selection of our coverage in the media, industry, latest developments, plus videos, and more.

Hospital Connection

On Wednesday, Helena Castillo Ecija PhD, MBA, our Preclinical and Clinical Project Manager, attended…

Marina Plaza – Meet the Team

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Meritxell Teixidó, one of the 20 recipients of the Jump Startup for Women in Deeptech program

Foment and the Consulate General of the United States presented the 20 entrepreneurs selected with the…

Research & Innovation Week Brussels

Since yesterday, Gate2Brain has been participating in Research & Innovation (R&I) Week, a flagship…

Gate2Brain, winner of the Senén Vilaró Award, explains its innovative technology

In light of receiving the Senén Vilaró Award, the University of Barcelona has crafted this brief video…

CataloniaBio HealthTech Gala 2024

Last night, Gate2Brain had the honor of attending the CataloniaBio HealthTech Gala with entrepreneurs,…

4YFN 2024

It has been a series of intense and enriching days at 4YFN, within the Catalonia Health Innovation Ecosystem…

Ricard Casanovas – Meet the Advisory Board!

We are continuing to introduce the remarkable individuals who make up Gate2Brain’s external advisory…

XVth SPLC-CRS Conference on Controlled Drug Delivery

Last week, Gate2Brain had the privilege of attending the XVth SPLC-CRS Conference on Controlled Drug…

International Childhood Cancer Day

San Joan de Déu Hospital - Family Assistance Program The daily routine of families with hospitalized…

Making therapies a reality for patients by addressing unmet medical needs.


Improving patients’ quality of life using a technology that provides superior drug transport efficacy.

Go Beyond Barriers & Contact Us

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Barcelona Scientific Park
Baldiri Reixac, 4-8, Torre I
08028 Barcelona, Spain